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M Zouhair Atassi Selected Research

Torticollis (Wryneck)

1/2018The Regions on the Light Chain of Botulinum Neurotoxin Type A Recognized by T Cells from Toxin-Treated Cervical Dystonia Patients. The Complete Human T-Cell Recognition Map of the Toxin Molecule.
1/2017Antibody responses to botulinum neurotoxin type A of toxin-treated spastic equinus children with cerebral palsy: A randomized clinical trial comparing two injection schedules.
11/2016Submolecular recognition regions of the HN domain of the heavy chain of botulinum neurotoxin type A by T cells from toxin-treated cervical dystonia patients.
4/2016Submolecular recognition of the C-terminal domain of the heavy chain of botulinum neurotoxin type A by T cells from toxin-treated cervical dystonia patients.
4/2015The C-terminal heavy-chain domain of botulinum neurotoxin a is not the only site that binds neurons, as the N-terminal heavy-chain domain also plays a very active role in toxin-cell binding and interactions.
7/2014Reduction of established antibody responses against botulinum neurotoxin A by synthetic monomethoxypolyethylene glycol peptide conjugates.
1/2012Molecular immune recognition of botulinum neurotoxin B. The light chain regions that bind human blocking antibodies from toxin-treated cervical dystonia patients. Antigenic structure of the entire BoNT/B molecule.
12/2011Human T-cell responses to botulinum neurotoxin. Responses in vitro of lymphocytes from patients with cervical dystonia and/or other movement disorders treated with BoNT/A or BoNT/B.
7/2011Regions of botulinum neurotoxin A light chain recognized by human anti-toxin antibodies from cervical dystonia patients immunoresistant to toxin treatment. The antigenic structure of the active toxin recognized by human antibodies.
6/2011Reduction of antibody response against botulinum neurotoxin A by synthetic monomethoxypolyethylene glycol-peptide conjugates.
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M Zouhair Atassi Research Topics

Disease

15Torticollis (Wryneck)
01/2018 - 03/2006
9Myasthenia Gravis
11/2017 - 05/2002
5Autoimmune Diseases (Autoimmune Disease)
11/2017 - 03/2005
3Experimental Autoimmune Myasthenia Gravis (Autoimmune Experimental Myasthenia Gravis)
09/2017 - 02/2006
2Movement Disorders (Movement Disorder)
12/2011 - 08/2011
1Necrosis
09/2017
1Muscle Spasticity (Spastic)
01/2017
1Cerebral Palsy (Spastic Diplegia)
01/2017
1Neuroblastoma
04/2015
1Paralysis (Palsy)
04/2015
1Dystonia (Limb Dystonia)
10/2009
1Inflammation (Inflammations)
03/2008
1Neoplasms (Cancer)
03/2008
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
03/2008
1Infections
03/2008
1Neuromuscular Diseases (Neuromuscular Disease)
01/2007
1Weight Loss (Weight Reduction)
06/2006
1Fatigue
06/2006
1Tremor (Tremors)
06/2006
1Whooping Cough (Pertussis)
02/2006
1Hemorrhage
08/2005
1Hypersensitivity (Allergy)
03/2005
1Wounds and Injuries (Trauma)
01/2005
1Tetanus
08/2002

Drug/Important Bio-Agent (IBA)

13incobotulinumtoxinAFDA Link
01/2018 - 08/2005
8Botulinum Toxins (Botulinum Toxin)IBA
01/2018 - 08/2002
8Type A Botulinum Toxins (Botox)FDA Link
01/2018 - 03/2006
7Peptides (Polypeptides)IBA
01/2018 - 01/2005
7AntibodiesIBA
04/2015 - 06/2006
5Cholinergic ReceptorsIBA
03/2012 - 05/2002
3Blocking AntibodiesIBA
01/2012 - 09/2008
2AntigensIBA
01/2018 - 01/2007
2Freund's AdjuvantIBA
09/2017 - 08/2017
2Immune Sera (Antisera)IBA
07/2011 - 08/2005
2Proteins (Proteins, Gene)FDA Link
03/2008 - 03/2005
2EpitopesIBA
03/2008 - 01/2007
2Histocompatibility Antigens Class IIIBA
01/2007 - 02/2006
1ThymidineIBA
01/2018
1tetanospasmin (tentoxilysin)IBA
01/2018
1Immunoglobulin FragmentsIBA
11/2017
1AutoantigensIBA
11/2017
1CytokinesIBA
09/2017
1Acetylcholine (Acetylcholine Chloride)FDA Link
04/2015
1AutoantibodiesIBA
03/2012
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
03/2012
1Tetanus ToxinIBA
12/2011
1rimabotulinumtoxinBFDA Link
09/2008
1Protein Tyrosine PhosphatasesIBA
03/2008
1Protein SIBA
03/2008
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2008
1HLA-DQ Antigens (HLA-DQ)IBA
06/2006
1muskIBA
06/2006
1Phosphotransferases (Kinase)IBA
06/2006
1HLA-DQA1 antigen (HLA DQA1)IBA
06/2006
1ToxoidsIBA
03/2006
1aluminum sulfate (alum)IBA
02/2006

Therapy/Procedure

3Injections
09/2017 - 02/2006
1Resuscitation
01/2005